A convenient regioselective synthesis of pyrano[3,2-b]acridones involving nucleophilic addition to benzyne

DOI: 10.1016/S0040-4039(99)01424-0

Source and publish data:

Tetrahedron Letters p. 7003 - 7006 (1999)

Update date:2022-07-30

Topics:

Authors:

Rudas, Monika

Nyerges, Miklos

Toeke, Laszlo

Pete, Bela

Groundwater, Paul W.

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Article abstract of DOI:10.1016/S0040-4039(99)01424-0

Acridone 8 was prepared by the nucleophilic addition of aniline 4 to benzyne 5. Hydrolysis of the ester group, followed by cyclisation gave the acridone 8, which was subsequently converted to the pyrano[3,2-b]acridin-4-ones 11 and 17.

Full text of DOI:10.1016/S0040-4039(99)01424-0

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