Condensed-purines syntheses of tetrahydro-1,4-diazepino[1,2,3-gh]purin- 2-one and hexahydro-1,4-diazocino[1,2,3-gh]purin-2-one

DOI: 10.1248/cpb.47.1322

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1322 - 1325 (1999)

Update date:2022-07-30

Topics:

Authors:

Suzuki, Hirokazu

Sawanishi, Hiroyuki

Yamamoto, Kenji

Miyamoto, Ken-Ichi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.47.1322

1,4-Pyrimido- (2a), 1,4-diazepino- (2b), and 1,4-diazocino[1,2,3- gh]purine (2c) were designed as selective cAMP-phosphodiesterase 4 (PDE 4) inhibitors. The desired condensed-purines (2b,c) were synthesized by reaction of 7-aminoalkyl-3-propylpurine-2,4-d

Full text of DOI:10.1248/cpb.47.1322

NII-Electronic Library Service

Products guided by the article

Product name:Carbamic acid, [4-(1,2,3,6-tetrahydro-2,6-dioxo-3-propyl-7H-purin-7-yl)butyl]-, phenylmethyl ester

Cas No:251918-43-1

R&D Labs maybe for 251918-43-1

LIDE PHARMACEUTICALS LIMITED

website:http://www.lidepharma.com

Contact:+86-25-58409506

Address:Chungking Express Nos.36 Nathan Road，Kowloon, HK
Shandong Yuanli Science and Technology Co., Ltd.

Contact:86-0536-6777557

Address:Zhuliu Industiral Park,Changle County
Hebei DaPeng Pharm & Chem Co., Ltd.

Contact:86-317-7298678,0576-88861898 88861908

Address:West Songmen Village, East Songmen Town, Wuqiao, Cangzhou, Hebei ,China
Wuxi Zuping Food Science And Technology Co.,LTD.

Contact:+86-510-87210822

Address:Guanlin town
HuiFeiChem PharmaTech Co.Ltd

Contact:0510-85393305

Address:1619 Huishan Avenue, Huishan District, Wuxi,

Relevant to this article

Synthesis and characterization of salts containing the BrO ₃F₂^- anion; a rare example of a bromine(VII) species

Doi:10.1021/ja0402607
(2005)
Reactions of New Osmium-Dihydride Complexes with Terminal Alkynes: Metallacyclopropene versus Metal-Carbyne. Influence of the Alkyne Substituent

Doi:10.1021/om990426q
(1999)
Self-assembly of amphoteric azopyridine carboxylic acids: Organized structures and macroscopic organized morphology influenced by heat, pH change, and light

Doi:10.1021/ja001790f
(2000)
Enantioselective Synthesis of Axially Chiral Biaryls by Diels-Alder/Retro-Diels-Alder Reaction of 2-Pyrones with Alkynes

Doi:10.1021/jacs.1c04759
(2021)
Synthesis and Atropo-diastereoselective Ring Cleavage of a [Cp*Ru]-Complexed Biaryl Lactone: Experimental and Computational Investigations

Doi:10.1021/om9906520
(1999)
A Convenient One-Pot Procedure to Arylcyclobutenes from Arylacetylenes

Doi:10.1021/jo990596c
(1999)

Article Doi