Chemical and Pharmaceutical Bulletin p. 1322 - 1325 (1999)
Update date:2022-07-30
Topics:
Suzuki, Hirokazu
Sawanishi, Hiroyuki
Yamamoto, Kenji
Miyamoto, Ken-Ichi
1,4-Pyrimido- (2a), 1,4-diazepino- (2b), and 1,4-diazocino[1,2,3- gh]purine (2c) were designed as selective cAMP-phosphodiesterase 4 (PDE 4) inhibitors. The desired condensed-purines (2b,c) were synthesized by reaction of 7-aminoalkyl-3-propylpurine-2,4-d
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Doi:10.1021/ja0402607
(2005)Doi:10.1021/om990426q
(1999)Doi:10.1021/ja001790f
(2000)Doi:10.1021/jacs.1c04759
(2021)Doi:10.1021/om9906520
(1999)Doi:10.1021/jo990596c
(1999)
