Synthesis of aspidospermidine alkaloids from 1,2,3,4- tetrahydrocarbazole: Total stereoselective synthesis of (±)-18- noraspidospermidine

Article abstract of DOI:10.1016/S0040-4020(99)00614-6

The reactivity of the 1,2,3,4-tetraliydrocarbazol-4-one derivatives has been analysed and applied to the synthesis of (±)-18-noraspidospennidine (1b). Tiffs was synthesised, starting from 4-(1',3'-dioxolan-2'- yl)cyclohexanone which was successively trans