7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 inhibitors: A potential treatment for asthma

DOI: 10.1016/S0960-894X(01)00786-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 509 - 512 (2002)

Update date:2022-07-30

Topics:

Authors:

Buckley, George M.

Cooper, Nicola

Davenport, Richard J.

Dyke, Hazel J.

Galleway, Fiona P.

Gowers, Lewis

Haughan, Alan F.

Kendall, Hannah J.

Lowe, Christopher

Montana, John G.

Oxford, Janet

Peake, Joanna C.

Picken Picken

Richard, Marianna D.

Sabin, Verity

Sharpe, Andrew

Warneck, Julie B.H.

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Article abstract of DOI:10.1016/S0960-894X(01)00786-7

The synthesis and pharmacological profile of a novel series of 7-methoxy-furo[2,3-c]pyridine-4-carboxamides is described. Some of these compounds were found to be potent inhibitors of phosphodiesterase type 4 (PDE4). Initial

Full text of DOI:10.1016/S0960-894X(01)00786-7

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Product name:2-ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester

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