Tetrahedron Letters p. 7721 - 7725 (1999)
Update date:2022-08-05
Topics:
Zhong, H. Marlon
Cohen, Judith H.
Abdel-Magid, Ahmed F.
Kenney, Birdella D.
Maryanoff, Cynthia A.
Shah, Rekha D.
Villani Jr., Frank J.
Zhang, Fan
Zhang, Xini
Methyl (S)-3-amino-3-(3-pyridyl)propanoate (2) is a key starting material in the synthesis of RWJ-53308 (1), an orally active antagonist of the platelet fibrinogen receptor (GP IIb/IIIa antagonist). Herein, we describe an efficient stereoselective synthes
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(1999)
