Tetrahedron Letters p. 9037 - 9040 (1999)
Update date:2022-08-04
Topics:
Ducrot, Pierre
Thal, Claude
trans 1-Aminoindolo[2,3-a]quinolizidines were synthesised using an intramolecular Pictet-Spengler-like reaction. Starting from commercially available N-Cbz-L-glutamic acid, indoloquinolizidines were obtained in only five steps with good yields. This improved synthesis is the result of both a highly regioselective imide reduction and a highly diastereoselective reaction using N-acyliminium ions.
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Doi:10.1016/S0040-4020(99)00941-2
(1999)Doi:10.1021/ol990372g
(2000)Doi:10.1021/ja993829q
(2000)Doi:10.1021/acsmedchemlett.0c00647
(2021)Doi:10.1039/a906553i
(1999)Doi:10.1039/d0cc06205g
(2020)
