
Tetrahedron Letters p. 9119 - 9120 (1999)
Update date:2022-09-26
Topics:
Hansen, Thomas Kruse
Preparations of aza analogues of known potent growth hormone secretagogues (GHS) were unsuccessful using known methods for preparation of azapeptides when hindered amines were employed. We now report a coupling method using bispentafluorophenylcarbonate as a 'balanced reactivity' phosgene equivalent to solve these problems.
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