Synthesis and characterization of intermediate and transition-state analogue inhibitors of γ-gutamyl peptide ligases

DOI: 10.1271/bbb.63.2248

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Bioscience, Biotechnology and Biochemistry p. 2248 - 2251 (1999)

Update date:2022-07-30

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Authors:

Inoue, Makoto

Hiratake, Jun

Sakata, Kanzo

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Article abstract of DOI:10.1271/bbb.63.2248

The phosphonodifluoromethyl ketone and phosphonofluoridate derivatives of L-glutamic acid were synthesized and characterized as analogues of the γ-glutamyl phosphate intermediate and the tetrahedral transition state, respectively, for the inhibition of γ-

Full text of DOI:10.1271/bbb.63.2248

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