Reactions of N-hydroxysuccinimide esters of anthranilic acids with anions of β-keto esters. A new route to 4-oxo-3-quinolinecarboxylic acid derivatives

DOI: 10.1248/cpb.48.211

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Chemical and Pharmaceutical Bulletin p. 211 - 214 (2000)

Update date:2022-08-03

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Authors:

Mitsos, Christos

Zografos, Alexandros

Igglessi-Markopoulou, Olga

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Article abstract of DOI:10.1248/cpb.48.211

A new approach for the synthesis of 4-oxo-3-quinolinecarboxylic acid derivatives is described. This methodology involves the C-acylation of the anions of appropriate β-keto esters with novel N-hydroxysuccinimide esters of anthranilic acids. The intermedia

Full text of DOI:10.1248/cpb.48.211

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