The synthesis of enantiomerically pure disubstituted aziridines and N- alkoxy aziridines

DOI: 10.1016/S0040-4039(99)02211-X

Source and publish data:

Tetrahedron Letters p. 787 - 790 (2000)

Update date:2022-08-05

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Authors:

Hanessian, Stephen

Cantin, Louis-David

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Article abstract of DOI:10.1016/S0040-4039(99)02211-X

The addition of a chloroallyl phosphonamide anion to oximes has allowed the preparation of a variety of cis-disubstituted N-alkoxy aziridines in enantiomerically pure form. Oxidative cleavage of the chiral auxiliary followed by derivatization of the products has allowed the preparation of enantiopure N-alkoxy aziridines. (C) 2000 Elsevier Science Ltd.

Full text of DOI:10.1016/S0040-4039(99)02211-X

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