An asymmetric synthesis of α-amino acid derivatives from racemic ethyl N-phenylsulphonyl-α-bromoglycinate using homochiral aluminium complexes

Article abstract of DOI:10.1016/0040-4039(96)00938-0

Reactions of a racemic α-bromoglycinate 2 with readily available alkyl aluminium reagents modified by binaphthol derivatives produce α-amino acid analogues 3 in high yields and with asymmetric induction of up to 62%.