Synthesis of oligodeoxynucleotides containing 4'-C-aminoalkylthymidines and their thermal stability and nuclease-resistance properties

Article abstract of DOI:10.1080/07328319908044731

To find the nuclease-resistant oligodeoxynucleotides (ODNs) with natural phosphodiester linkages, we designed and synthesized ODNs containing 4'-C- aminoalkylthymidines (1-4). We found that the ODNs containing 1, 2, 3 or 4 were more resistant to nucleolyt

Full text of DOI:10.1080/07328319908044731

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Nucleosides and Nucleotides
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Synthesis of Oligodeoxynucleotides
Containing 4′-C-Aminoalkyl-thymidines
and Their Thermal Stability and
Nuclease-Resistance Properties
Yoshihito Ueno a , Makiko Kanazaki a , Satoshi Shuto a & Akira
Matsuda a
a Graduate School of Pharmaceutical Sciences, Hokkaido University,
Kita-12, Nishi-6, Kita-ku, Sapporo, 060-0812, Japan
Published online: 04 Oct 2006.
To cite this article: Yoshihito Ueno , Makiko Kanazaki , Satoshi Shuto & Akira Matsuda (1999):
Synthesis of Oligodeoxynucleotides Containing 4′-C-Aminoalkyl-thymidines and Their Thermal Stability
and Nuclease-Resistance Properties, Nucleosides and Nucleotides, 18:6-7, 1401-1402
To link to this article: http://dx.doi.org/10.1080/07328319908044731
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