2-(3-pyridyl)thiazolidine-4-carboxamide derivatives. II. Structure- activity relationships and active configuration of 2-(3- pyridyl)thiazolidine-4-carboxamides as platelet-activating factor receptor antagonists

DOI: 10.1248/cpb.46.1468

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1468 - 1473 (1998)

Update date:2022-07-30

Topics:

Authors:

Suzuki, Takeshi

Nagaoka, Hitoshi

Kondo, Yutaka

Takahashi, Takumi

Takeuchi, Makoto

Hara, Hiromu

Saito, Munetoshi

Yamada, Toshimitsu

Tomioka, Kenichi

Hamada, Mamoru

Mase, Toshiyasu

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Article abstract of DOI:10.1248/cpb.46.1468

Conversion of the 2-(3-pyridyl)thiazolidine part of 1-(3-phenylpropyl)- 4-[2-(3-pyridyl)thiazolidine-4-carbonyl]piperazine (YM461), which is a potent platelet-activating factor (PAF) antagonist, to other rings was performed, and PAF antagonistic activitie

Full text of DOI:10.1248/cpb.46.1468

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