Stereoselective Synthesis of Dipeptides by Asymmetric Reduction of Dehydropeptides Catalyzed by Chiral Rhodium Complexes

Article abstract of DOI:10.1021/jo01311a026

Asymmetric catalysis was used to control the creation of an asymmetric center in a chiral dehydropeptide.The reduction of Ac-ΔPhe-(S)-Phe-OR (R=H or Me) was studied as a model.Depending on the type of chiral rhodium catalyst used, it was possible to selec