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ChemComm
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DOI: 10.1039/C6CC08891K
COMMUNICATION
Journal Name
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17 Recently, advantages from flow technology have proven
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which results in highly chemoselective transfer of N and O
groups. The reaction tolerates varied sulfur substituents and
functional groups. The developed strategy also allowed the
15N-labeling of NH-sulfoximines. Preliminary mechanistic
investigations suggest the introduction of the nitrogen
followed by the oxidation of the resulting sulfilimine.
This research was supported by Regione Puglia: "Reti di
Laboratori pubblici di ricerca" (Projects code 20, 68). Project
Laboratorio Sistema code PONa300369 financed by MIUR, the
University of Bari. We gratefully acknowledge The Royal
Society for a University Research Fellowship (to J.A.B.), EPSRC
[CAF to J.A.B. (EP/J001538/1), Impact Acceleration Account
(EP/K503733/1), DTA Studentship (to S.S.J.C)]. We thank Dr
Manuel Cases-Thomas (Eli Lilly) for valuable discussion and Eli
Lilly for studentship funding (to S.J.C.). We acknowledge the
EPSRC National Mass Spectrometry Facility, Swansea. We are
grateful to Dr. Cosimo Cardellicchio (ICCOM-CNR Bari) and
Chiara Zucaro (University of Bari) for their contribution.
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4 | J. Name., 2012, 00, 1-3
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