One-pot preparation of 1-substituted imidazole-2-thione from isothiocyanate and amino acetal

Article abstract of DOI:10.1080/00397919708007078

Isothiocyanates were treated with amino acetal and cone. HCl (0.5 eq.) successively in one-pot to afford 1-substituted imidazole-2-thiones in good yields.

Full text of DOI:10.1080/00397919708007078

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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One-Pot Preparation of 1-
Substituted Imidazole-2-thione
from Isothiocyanate and Amino
Acetal
Koyo Matsuda a , Isao Yanagisawa a , Yasuo Isomura a
, Toshiyasu Mase a & Tadao Shibanuma a
a Institute for Drug Discovery Research, Yamanouchi
Pharmaceutical Co. Ltd., 21 Miyukigaoka, Tsukuba,
Ibaraki, 305, JAPAN
Version of record first published: 22 Aug 2006.
To cite this article: Koyo Matsuda , Isao Yanagisawa , Yasuo Isomura , Toshiyasu Mase
& Tadao Shibanuma (1997): One-Pot Preparation of 1-Substituted Imidazole-2-thione
from Isothiocyanate and Amino Acetal, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 27:20, 3565-3571
To link to this article: http://dx.doi.org/10.1080/00397919708007078
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