Synthesis of 9Z-9-substituted retinoic acids by palladium catalyzed coupling reaction of a vinyl triflate with alkenyl stannanes

DOI: 10.1248/cpb.48.1391

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1391 - 1394 (2000)

Update date:2022-07-29

Topics:

Authors:

Wada Wada

Nomoto Nomoto

Tano Tano

Yamashita

Ito Ito

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Article abstract of DOI:10.1248/cpb.48.1391

Palladium catalyzed cross coupling reactions of a vinyl triflate intermediate and various alkenyl stannanes afforded trisubstituted Z-olefins stereoselectively in high yields. These olefins were then converted to the corresponding 9Z-retinoic acids via Ho

Full text of DOI:10.1248/cpb.48.1391

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