Synthesis of the key disaccharide of 3'-sulfo Lewis X and Lewis A: The novel E-selectin ligand

Article abstract of DOI:10.1080/00397910008087007

Benzyl 2,4,6-tri-O-benzyl-β-D-galactopyranoside (6) was synthesised from regioselective protection of stannylated benzyl 2,6-di-O-benzyl -β-D-galactopyranoside (3) with 4-methoxybcnzyl chloride, followed by benzylation and oxidative removal of the temporary protecting group. The disaccharide (2) was prepared by condensation of the common acceptor 6 with 7 through thial activation as well as with 8 following Konigs Knorr procedure.

Full text of DOI:10.1080/00397910008087007

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Synthetic Communications: An
International Journal for Rapid
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Synthesis of the Key
Disaccharide of 3′-Sulfo Lewis
X and Lewis A: The Novel E-
Selectin Ligand
U. S. Chowdhury a
a Indian Institute of Chemical Biology 4 , Raja S. C.
Mullick Road, Calcutta, 700 032, India
Published online: 04 Dec 2007.
To cite this article: U. S. Chowdhury (2000) Synthesis of the Key Disaccharide of 3′-
Sulfo Lewis X and Lewis A: The Novel E-Selectin Ligand, Synthetic Communications:
An International Journal for Rapid Communication of Synthetic Organic Chemistry,
30:20, 3785-3792, DOI: 10.1080/00397910008087007
To link to this article: http://dx.doi.org/10.1080/00397910008087007
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