Characterization and mechanistic studies of DesII: A radical S-adenosyl-l-methionine enzyme involved in the biosynthesis of TDP-D-desosamine

DOI: 10.1021/ja903354k

Source and publish data:

Journal of the American Chemical Society p. 14030 - 14042 (2009)

Update date:2022-08-04

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Authors:

Szu, Ping-Hui

Ruszczycky, Mark W.

Choi, Sei-Hyun

Yan, Feng

Liu, Hung-Wen

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Article abstract of DOI:10.1021/ja903354k

D-Desosamine (1) is a 3-(N,N-dimethylamino)-3,4,6-trideoxyhexose found in a number of macrolide antibiotics including methymycin (2), neomethymycin (3), pikromycin (4), and narbomycin (5) produced by Streptomyces venezuelae. It plays an essential role in

Full text of DOI:10.1021/ja903354k

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