Quinolone antimicrobial agents substituted with morpholines at the 7- position. Syntheses and structure-activity relationships

Article abstract of DOI:10.1021/jm00062a007

A series of novel 7-substituted 1-cyclopropyl-6,8-difluoro-1,4-dihydro-4- oxo-3-quinolinecarboxylic acids have been prepared and tested for antibacterial activities and for convulsive activities in combination with nonsteroidal antiinflammatory drug. Stru