European Journal of Medicinal Chemistry p. 553 - 560 (1988)
Update date:2022-08-05
Topics:
Ronsisvalle, Giuseppe
Pappalardo, Maria S.
Vittorio, Franco
Pasquinucci, Lorella
Caruso, Antonina
et al.
A series of N-thienylalkylenediamines was synthesized and tested for their analgesic, anti-inflammatory and anti-pyretic activities, as well as for their acute toxicity and central effects.Acetylsalicylic acid, phenylbutazone and indomethacin were used as reference drugs.Several compounds showed interesting aspirin-like properties associated with good systemic and gastric tolerance.Keywords: 2-nitrothiophenes / N-thienyl alkylenediamines / anti-inflammatory activity / analgesic activity / basic anti-inflammatory agents
View MoreCHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD
website:http://www.czyys.com
Contact:0086-519-88802789
Address:No.300,Yanling Middle Road, Changzhou, Jiangsu, China
website:http://www.mingchem.com/en/index
Contact:0519-85170101-802
Address:Fifth Floor,B of Beihua Buliding,520 Road of Science and Education City,Changwu middle road NO.801,Wujin District,Changzhou,Jiangsu province
Zhejiang Sucon Silicone Co.,Ltd
Contact:+86-575-88046692
Address:Qisheng Rd., Paojiang Industrial Zone, Shaoxing, Zhejiang, China.
Xinjiang Fufeng Biotechnologies Co., Ltd.
Contact:+86-539-7287111
Address:GANQUANPU INDUSTRIAL PARK, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT AREA (TOUTUNHE DISTRICT) OF URUMQI
Contact:86-371-63655023
Address:No.85,jinshui road,zhengzhou,China
Doi:10.1021/jo00820a024
(1971)Doi:10.1007/PL00010131
(1998)Doi:10.1021/acs.orglett.9b03990
(2019)Doi:10.1246/bcsj.43.3287
(1970)Doi:10.1021/jm010100v
(2001)Doi:10.1002/chem.200901046
(2009)
