Chemical and Pharmaceutical Bulletin p. 1549 - 1557 (2000)
Update date:2022-08-04
Topics:
Saito
Tachi
Seki
Kamayachi
Kubo
A practical synthesis of 1,2,3,4,5,6-hexahydro-1,5-imino-10-hydroxy-9-methoxy-3,8,11-trimethyl-3-benza zocin-4-one (3) as an ABC ring model compound of ecteinascidin 743 and safracins from 3-hydroxy-4-methoxy-5-methylbenzaldehyde (7) is described. The overall yield in 15 step is 27%.
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Doi:10.1016/S0040-4039(00)01187-4
(2000)Doi:10.1021/op100291g
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(1972)Doi:10.1063/1.478826
(1999)Doi:10.1080/00397919808006842
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