Bull. Russ. Acad. Sci. Div. Chem. Sci. (Engl. Transl.) p. 2068 - 2073 (1992)
Update date:2022-09-26
Topics: Regioselectivity Yield Addition reaction Chromatography Nucleophilic substitution Kinetics Aromaticity Reaction Mechanism Solvent Effects Substituent Effects Stereoselectivity Catalysis Reaction Optimization Spectroscopic Analysis Pyrazole Derivatives Heterocyclic compound Electrophilic Electron-withdrawing group Thermodynamics
Golubev, A. S.
Tyutin, V. Yu.
Chkanikov, N. D.
Kolomiets, A. F.
Fokin, A. V.
Pyrazole derivatives were hydroxyalkylated at the C4 atom by hexafluoroacetate and methyl trifluoropyruvate.The products of the hydroxyalkylation were dehydrated to the corresponding alkylidene derivatives which were reacted with nucleophiles.D
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