
Bulletin of the Chemical Society of Japan p. 2759 - 2762 (1981)
Update date:2022-08-03
Topics:
Sawai, Hiroaki
Ohno, Masaji
Oligoinosinates up to a pentamer were synthesized by the polymerization of inosine-5'-phosphorimidazolide in aqueous solution using Pb2+ ion. 2'-5' Internucleotide linkage was preferentially formed.The yields of the 2'-5' linked dimer, trimer, and tetramer were 14.8, 4.5, and 1.6percent, respectively.A small amount of linkage isomers of oligoinosinates with 3'-5' linkage was obtained.The products were characterized by sequential enzyme tests.
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(1980)