Synthesis and tumor-promoting activities of 12-Epi-phorbol-12,13-dibutyrate.

DOI: 10.1271/bbb.64.2429

Source and publish data:

Bioscience, Biotechnology and Biochemistry p. 2429 - 2436 (2000)

Update date:2022-09-26

Topics:

Authors:

Irie Irie

Nakahara

Ikawa Ikawa

Tanaka Tanaka

Nakagawa

Nakamura

Ohigashi

Wender Wender

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Article abstract of DOI:10.1271/bbb.64.2429

12-Epi-phorbol-12,13-dibutyrate (1), the C12-epimer of the most frequently used phorbol ester probe, phorbol-12,13-dibutyrate (PDBu), has been synthesized from phorbol in 9 steps in order to investigate the structural requirements for tumor-promoting acti

Full text of DOI:10.1271/bbb.64.2429

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Product name:Butyric acid (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9-trihydroxy-1,1,6,8-tetramethyl-5-oxo-3-trityloxymethyl-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl ester

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