Derives alkyles et aryles de l'acide nipecotique: synthese et appreciation de l'activite inhibitrice de la capture du GABA en fonction de parametres conformationnels et de biodisponibilite

Article abstract of DOI:10.1016/0223-5234(87)90025-0

Alkyl and aryl derivatives of nipecotic acid: synthesis and inhibition of GABA uptake as a function of conformational parameters and bioavailability.Analogs of nipecotic acid, substituted at positions 2, 3, 4, 5, or 6 with a methyl or phenyl group were pr