Tetrahedron Letters p. 1819 - 1823 (2000)
Update date:2022-08-04
Topics:
Sakamoto, Katsuji
Honda, Erina
Ono, Noboru
Uno, Hidemitsu
An intramolecular acyl transfer reaction took place on treatment of 1- methoxymethoxy-3-(2-alkynoyloxy)methyl-2-iodonaphthalenes with n-BuLi at - 78°C to give 1-methoxymethoxy-2-alkynoyl-3-hydroxymethylnaphthalenes in high yields. After protection of the hydroxymethyl group as benzoates, formation of a γ-pyrone ring was easily achieved by deprotection of the MOM group followed by spontaneous 6-endo-digonal ring closure under mild acidic conditions. (C) 2000 Elsevier Science Ltd.
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Doi:10.1021/ja069372j
(2007)Doi:10.1002/1521-3773(20010316)40:6<1090::AID-ANIE10900>3.0.CO;2-W
(2001)Doi:10.1007/BF00950024
(1982)Doi:10.1016/S0022-328X(00)89507-8
(1975)Doi:10.1021/ja00525a025
(1980)Doi:10.1055/s-0042-118860
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