Syntheses of Aryl Glyoxylate. I. The Reaction of Alkyl Dichloro(alkoxy)acetates with Aromatics in the Presence of Lewis Acid

DOI: 10.1246/bcsj.57.810

Source and publish data:

Bulletin of the Chemical Society of Japan p. 810 - 814 (1984)

Update date:2022-08-05

Topics:

Authors:

Itoh, Osamu

Nagata, Takayoshi

Nomura, Isamu

Takanaga, Tetsuya

Sugita, Toshio

Ichikawa, Katsuhiko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/bcsj.57.810

Ethyl dichloro(ethoxy)acetate(1) and methyl dichloro(methoxy)acetate(2) were characterized.The reaction of 1 and 2 with aromatics in the presence of AlCl₃ gave a considerable yield of aromatic α-keto ester.The aromatics included mono- and polymethylbenzene and anisol.The reaction was studied under various conditions and the results were compared with the acylation by ethoxalyl or methoxalyl chloride.The reaction mechanism was also discussed.

Full text of DOI:10.1246/bcsj.57.810

Products guided by the article

Product name:methyl 2,4,6-trimethylphenylgloxylate

Cas No:34404-83-6

R&D Labs maybe for 34404-83-6

SPRING CHEMICAL INDUSTRY CO.,LTD

Contact:86-187-66672125

Address:linchi industry park.zouping
SuZhou LaiTeou

Contact:+86-0512-88957371

Address:shanghai
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Contact:+86-21-5161 3915

Address:Shanghai YangPu
SOGA ENTERPRISES ASIA GROUP

Contact:+86-633-8332928

Address:No.1,Huanghai Yilu.Rizhao,Shandong
Wuhan Shengmao Corp

website:http://www.shengmaochem.com

Contact:86-27-82853423, 82819281

Address:Rm 202, A Unit Huaqiao Building No. 2, Lihuangpi Road, Wuhan, China

Relevant to this article

1,3-Dipolar cycloaddition reactions of organic azides with morpholinobuta-1,3-dienes and with an α-ethynyl-enamine

Doi:10.1002/hlca.200590142
(2005)
Enantioselective total synthesis of salicylihalamides A and B

Doi:10.1016/S0040-4039(01)00278-7
(2001)
Doi:10.1021/jo00978a034
(1972)
Half-sandwich complexes of titanium and zirconium with pendant phenyl substituents. The influence of ansa-aryl coordination on the polymerisation activity of half-sandwich catalysts

Doi:10.1016/S0022-328X(99)00488-X
(1999)
Direct synthesis of previously inaccessible bridgehead azabicyclics by intramolecular cyclization of α-sulfonamido and α-sulfonimido radicals

Doi:10.1021/jo010216z
(2001)
Modifying a composite based on silica molecular sieve and a Ru(II)-based probe with Fe₃O₄ particles: Construction and oxygen sensing performance

Doi:10.1016/j.ica.2016.02.061
(2016)

Article Doi