Syntheses of Aryl Glyoxylate. I. The Reaction of Alkyl Dichloro(alkoxy)acetates with Aromatics in the Presence of Lewis Acid

DOI: 10.1246/bcsj.57.810

Source and publish data:

Bulletin of the Chemical Society of Japan p. 810 - 814 (1984)

Update date:2022-08-05

Topics:

Authors:

Itoh, Osamu

Nagata, Takayoshi

Nomura, Isamu

Takanaga, Tetsuya

Sugita, Toshio

Ichikawa, Katsuhiko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/bcsj.57.810

Ethyl dichloro(ethoxy)acetate(1) and methyl dichloro(methoxy)acetate(2) were characterized.The reaction of 1 and 2 with aromatics in the presence of AlCl₃ gave a considerable yield of aromatic α-keto ester.The aromatics included mono- and polymethylbenzene and anisol.The reaction was studied under various conditions and the results were compared with the acylation by ethoxalyl or methoxalyl chloride.The reaction mechanism was also discussed.

Full text of DOI:10.1246/bcsj.57.810

Products guided by the article

Product name:methyl 2,4,6-trimethylphenylgloxylate

Cas No:34404-83-6

R&D Labs maybe for 34404-83-6

Suqian Ruixing Chemical Co., Ltd.

Contact:+86-527-80805666（总机）;84836008(销售)

Address:3 Jingsilu, Zone north, Hubin Xincheng Development Park, Suqian, China
BIOS CHEMICALS

Contact:+33-5-34012600

Address:28 ZA des Pignès
Shanghai birch chemical technology co.,ltd

Contact:+86-21-54096810

Address:No.2588,Jungong Road,Shanghai,China
Jinan Baozhao Pharmaceutical Co., Ltd

Contact:0086-531-86397156 82371858 82371868

Address:Huaneng Road, Jinan, Shandong ,China
Guangzhou Shiny Co., Ltd.

website:https://www.sinoshiny.com/products

Contact:+86-20-62802632;62802633

Address:Room 330 GIGCAS Building,No.511 Kehua Street,Tianhe District

Relevant to this article

1,3-Dipolar cycloaddition reactions of organic azides with morpholinobuta-1,3-dienes and with an α-ethynyl-enamine

Doi:10.1002/hlca.200590142
(2005)
Enantioselective total synthesis of salicylihalamides A and B

Doi:10.1016/S0040-4039(01)00278-7
(2001)
Doi:10.1021/jo00978a034
(1972)
Half-sandwich complexes of titanium and zirconium with pendant phenyl substituents. The influence of ansa-aryl coordination on the polymerisation activity of half-sandwich catalysts

Doi:10.1016/S0022-328X(99)00488-X
(1999)
Direct synthesis of previously inaccessible bridgehead azabicyclics by intramolecular cyclization of α-sulfonamido and α-sulfonimido radicals

Doi:10.1021/jo010216z
(2001)
Modifying a composite based on silica molecular sieve and a Ru(II)-based probe with Fe₃O₄ particles: Construction and oxygen sensing performance

Doi:10.1016/j.ica.2016.02.061
(2016)

Article Doi