Syntheses of Aryl Glyoxylate. I. The Reaction of Alkyl Dichloro(alkoxy)acetates with Aromatics in the Presence of Lewis Acid

DOI: 10.1246/bcsj.57.810

Source and publish data:

Bulletin of the Chemical Society of Japan p. 810 - 814 (1984)

Update date:2022-08-05

Topics:

Authors:

Itoh, Osamu

Nagata, Takayoshi

Nomura, Isamu

Takanaga, Tetsuya

Sugita, Toshio

Ichikawa, Katsuhiko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/bcsj.57.810

Ethyl dichloro(ethoxy)acetate(1) and methyl dichloro(methoxy)acetate(2) were characterized.The reaction of 1 and 2 with aromatics in the presence of AlCl₃ gave a considerable yield of aromatic α-keto ester.The aromatics included mono- and polymethylbenzene and anisol.The reaction was studied under various conditions and the results were compared with the acylation by ethoxalyl or methoxalyl chloride.The reaction mechanism was also discussed.

Full text of DOI:10.1246/bcsj.57.810

Products guided by the article

Product name:methyl 2,4,6-trimethylphenylgloxylate

Cas No:34404-83-6

R&D Labs maybe for 34404-83-6

Beijing Zhongshuo Pharmaceutical T & D Co.,Ltd

Contact:0086-10-64430626

Address:ea No 16, HEPINGLI,DONGCHENG DISTRICT,BEIJING,P.R.CHINA.
Zhejiang Golden-Shell Pharmaceutical Co.,Ltd.

Contact:+86-576-87501888 / 87501988

Address:No.89 Zhongxing Road. Li'ao, Yuhuan, Zhejiang, China
C-LAB Chemievermittlung GmbH

Contact:+49-9398-993127

Address:Untertorstr. 27
Shenzhen Hongyuan Import & Export Co., Ltd.

Contact:0755-26407171

Address:Shenzhen Hongyuan Chemical New Materials Technology Co., Ltd.
Liao Cheng All Win Chemicals Co.,LTD

Contact:86+0635-2991582

Address:Room 402,Unit 1,No.27 building.Zhong tong shi dai haoyuan,liaocheng city,Shan dong Province.China

Relevant to this article

1,3-Dipolar cycloaddition reactions of organic azides with morpholinobuta-1,3-dienes and with an α-ethynyl-enamine

Doi:10.1002/hlca.200590142
(2005)
Enantioselective total synthesis of salicylihalamides A and B

Doi:10.1016/S0040-4039(01)00278-7
(2001)
Doi:10.1021/jo00978a034
(1972)
Half-sandwich complexes of titanium and zirconium with pendant phenyl substituents. The influence of ansa-aryl coordination on the polymerisation activity of half-sandwich catalysts

Doi:10.1016/S0022-328X(99)00488-X
(1999)
Direct synthesis of previously inaccessible bridgehead azabicyclics by intramolecular cyclization of α-sulfonamido and α-sulfonimido radicals

Doi:10.1021/jo010216z
(2001)
Modifying a composite based on silica molecular sieve and a Ru(II)-based probe with Fe₃O₄ particles: Construction and oxygen sensing performance

Doi:10.1016/j.ica.2016.02.061
(2016)

Article Doi