Advanced Synthesis and Catalysis p. 314 - 320 (2016)
Update date:2022-07-30
Topics:
Sharma, Nidhi
Sekar, Govindasamy
A binaphthyl-supported Pd nanoparticles (Pd-BNP)-catalyzed aminocarbonylation of aryl iodides in the presence of carbon monoxide and amines for the synthesis of amides has been developed. This methodology provides an efficient route for the synthesis of a COX-2 enzyme inhibitor having anti-inflammatory activity.
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Doi:10.1021/jo01305a004
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