A Convenient Synthesis of Amides with 2-Halo-2,3-dihydro-1,3,4,2-oxadiazaphospholes as a New Condensing Agents

Article abstract of DOI:10.1246/bcsj.66.327

Various amides, including some with bulky substituents, are prepared in good yields from free carboxylic acids and amines under mild conditions by a one-step method using new condensing agents 2-halo-2,3-dihydro-1,3,4,2-oxadiazaphospholes, especially 5-methyl-2-chloro-3-phenyl-2,3-dihydro-1,3,4,2-oxadiazaphosphole.