
Tetrahedron Letters p. 1687 - 1690 (1980)
Update date:2022-08-03
Topics:
Kleingeld
Nibbering
It is shown by 18O labelling that phenoxide anions are formed both by an SN2 and a nucleophilic aromatic substitution mechanism in the reaction of OH- with methyl phenyl ether. These mechanisms are of minor importance in the ethyl phenyl ether system where phenoxide anions are generated almost exclusively by an E2 mechanism.
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