Tetrahedron p. 8153 - 8160 (1990)
Update date:2022-07-30
Topics:
Katritzky, Alan R.
Long, Qiu-He
Lue, Ping
Jozwiak, Andrzej
A new, facile preparation of enamines was achieved via a two-step sequence: (i) the ready formation of an N-(α-aminoalkyl)benzotriazole derivative from equimolar amounts of benzotriazole, an aldehyde, and a secondary amine, (ii) the elimination of benzotriazole from the derivative by sodium hydride in tetrahydrofuran (THF).The method provides enamines in good yields based on the quantity of amine used.
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