Tetrahedron p. 4153 - 4157 (1984)
Update date:2022-09-26
Topics:
Cooper
Humber
Laundon
et al.
Potoinitiated bromination of the 1S-oxide ester 9, available in two stages from penicillin G6, gave the diastereometic bromides 10a and 10b. Both isomers have been utilized in further transformations to give the established antibiotics ampicillin 7 and cephalexin 8.
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