Observations on the nature of the tethering chain in the synthesis of biaryls and heterobiaryls via intramolecular free radical ipso substitution reactions

Article abstract of DOI:10.1016/S0040-4039(96)02237-X

A study of benzylic sulfonates and their corresponding N-methylsulphonamide derivatives as substrates in potential free radical [1,6] ipso substitution reactions reveals a preference for the alternative [1,7] addition mode. Empirical guidelines for biaryl