Journal of Medicinal Chemistry p. 3236 - 3245 (1995)
Update date:2022-08-05
Topics:
Atwal, Karnail S.
Grover, Gary J.
Ahmed, Syed Z.
Sleph, Paul G.
Dzwonczyk, Steven
et al.
Structure-activity relationships for the cyanoguanidine portion of the lead cardiac selective ATP-sensitive potassium channel (KATP) opener (3) are described.The cyanoguanidine moiety appears to be optimal since increasing or decreasing the dis
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