Synthesis of Macrotetrolide α, a Designed Polynactin Analog Composed of (+)- and (-)-Bishomononactic Acids

Article abstract of DOI:10.1271/bbb.65.2118

Macrotetrolide α, a designed analog of polynactin composed of (+)- and (-)-bishomononactic acids, was synthesized. These monomers were prepared via optical resolution of the corresponding (S)-O-acetylmandelates. Assembly of the monomers to macrotetrolide a look seven steps without any loss of the intermediates.

Full text of DOI:10.1271/bbb.65.2118

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Bioscience, Biotechnology, and Biochemistry
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Synthesis of Macrotetrolide α, a Designed Polynactin
Analog Composed of (+)- and (-)-Bishomononactic
Acids
Tadaatsu HANADATEa, Hiromasa KIYOTAa & Takayuki ORITANIa
a Laboratory of Applied Bioorganic Chemistry, Division of Life Science, Graduate School
of Agricultural Science, Tohoku University
Published online: 22 May 2014.
To cite this article: Tadaatsu HANADATE, Hiromasa KIYOTA & Takayuki ORITANI (2001) Synthesis of Macrotetrolide α, a
Designed Polynactin Analog Composed of (+)- and (-)-Bishomononactic Acids, Bioscience, Biotechnology, and Biochemistry,
65:9, 2118-2120, DOI: 10.1271/bbb.65.2118
To link to this article: http://dx.doi.org/10.1271/bbb.65.2118
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