Synthetic Communications p. 985 - 992 (1993)
Update date:2022-07-30
Topics:
Fryer
Zhang
Rios
The synthesis of substituted 2-aminophenyl heterocyclic ketones, key intermediates to the preparation of 1,4-benzodiazepines has been achieved in one step and in good, yield from the corresponding anthranilic acid, by treatment with heterocyclic lithium reagents and chlorotrimethylsilane.
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(1982)