The synthesis of substituted 2-aminophenyl heterocycic ketones

Article abstract of DOI:10.1080/00397919308013295

The synthesis of substituted 2-aminophenyl heterocyclic ketones, key intermediates to the preparation of 1,4-benzodiazepines has been achieved in one step and in good, yield from the corresponding anthranilic acid, by treatment with heterocyclic lithium reagents and chlorotrimethylsilane.