Heteroaromatization with ketene dithioacetals: Part II. Synthesis of some novel 5-aminopyrazole-3-carbonitrile, 3-carboxamide and pyrazolo[3,4-d]pyrimidin-4-one derivatives as antimicrobial agents

Article abstract of DOI:10.1080/10426500108040260

Ketene dithioacetals 1a-d are utilized for synthesis of pyrazoledithiocarboxylates 2a-d and arylaminopyrazoles 4a,b with two different substituents (o-ethoxy and p-diethylaminosulfonyl) in aryl residue. Some transformation of the dithioesters 2 are described. After that arylaminopyrazoles 4a,b are converted to pyrazolopyrimidine derivatives 8-11.