UNUSUAL CONJUGATE ADDITION OF ORGANOLITHIUM REAGENT TO α,β-UNSATURATED KETONE

Article abstract of DOI:10.1016/S0040-4039(00)96824-2

The conjugate addition of organolithium reagent to α,β-unsaturated ketone has been accomplished with methylaluminum bis(2,6-di-tert-butyl-4-alkylphenoxide) (MAD and MAT).Here combination of alkyllithium and MAD (or MAT) constitutes an amphiphilic system that allows to exhibit unusual selectivity in the alkylation of enones with alkyllithium.