Bioorganic and Medicinal Chemistry Letters p. 3793 - 3796 (2003)
Update date:2022-08-05
Topics:
Dyck, Brian
Parker, Jessica
Phillips, Teresa
Carter, Lee
Murphy, Brian
Summers, Robin
Hermann, Julia
Baker, Tracy
Cismowski, Mary
Saunders, John
Goodfellow, Val
Incorporation of substituted phenyl piperazine privileged structures into a known MC4 specific dipeptoid consensus sequence resulted in a series of potent (EC50=24 nM) and selective MC4-R agonists. We report the SAR of this series of compounds
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