The tert-butyl side chain: A powerful means to lock peptoid amide bonds in the cis conformation

DOI: 10.1021/ol400820y

Source and publish data:

Organic Letters p. 2246 - 2249 (2013)

Update date:2022-09-26

Topics:

Authors:

Roy Roy

Caumes Caumes

Esvan Esvan

Didierjean

Faure Faure

Taillefumier

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Article abstract of DOI:10.1021/ol400820y

The very simple sterically hindered tert-butyl side chain exerts complete control over the peptoid amide geometry which only exists in the cis conformation. It is exemplified in NtBu glycine homo-oligomers and in linear oligopeptoids designed with an alte

Full text of DOI:10.1021/ol400820y

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