Tetrahedron p. 14233 - 14254 (1998)
Update date:2022-09-26
Topics:
Jiang, Lu
Davison, Amanda
Tennant, George
Ramage, Robert
An optimal coupling reagent, ethyl 1-hydroxy-1H-1,2,3-triazole-4- carboxylate (HOCt), has been designed and synthesised for application to solid phase peptide synthesis using Fmoc chemistry. It is used in combination with carbodiimide reagents, has very high coupling efficiency, and does not absorb at 302nm, thus allowing real-time monitoring of each coupling cycle. Its applications in the synthesis of endothelin analogues and difficult sequences are also discussed.
View MoreBeijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)
website:http://www.bjgreenchem.com/
Contact:+86-427-6515887
Address:301,302, 3rd Floor, Building C-7, Dongsheng Science Park, Northern Territory, Zhongguancun, No. 66, Xixiaokou Road, Haidian District, Beijing
Onlychem (Jinan)Biotech Co.,Ltd
Contact:86-531-83175885
Address:No. 44, Honglou South Road, Jinan,China
Contact:+86-158-05817090
Address:ROOM 9F, FLAT 2, GUODU DEVELOPING BLDG, No.182, ZHAOHUI ROAD
Taizhou YOJOY Chemical Co., Ltd.
Contact:13857143241
Address:Yangfu Industrial Park, Xianju, Zhejiang, P. R. China
Yancheng Creator Chemical Co., Ltd
Contact:0086-515-88710008 88710068 88710858 88710868
Address:No.21 Renming Road, Longgang Town, Yandu County,Yancheng City
Doi:10.1021/acs.orglett.6b00817
(2016)Doi:10.1021/ja01593a043
(1956)Doi:10.1021/ja00531a024
(1980)Doi:10.1021/jo049794g
(2004)Doi:10.1016/j.tet.2003.11.053
(2004)Doi:10.1016/S0040-4039(00)76313-1
(1968)
