Journal of Organic Chemistry p. 6769 - 6775 (2018)
Update date:2022-08-04
Topics:
Feng, Bin
Li, Yang
Li, Huan
Zhang, Xu
Xie, Huamei
Cao, Hongen
Yu, Lei
Xu, Qing
A specific N-alkylation of 2-hydroxypyridines is achieved by reacting with organohalides under catalyst- and base-free conditions. The observed HX-facilitated conversion of pyridyl ether intermediates to 2-pyridone products may account for the success and
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