HYDRODEHALOGENATION OF BROMO- AND CHLOROPYRIDINES OVER PALLADIUM COMPLEX AND PALLADIUM METAL CATALYSTS

Article abstract of DOI:10.1007/BF00515028

The hydrodehalogenation of 2-chloro-, 2-bromo-, 3-bromo, and 3,5-dibromopyridine has been studied in the presence of a palladium complex catalyst immobilized on silica gel, and a Pd/C catalyst.Cleavage of bromine from bromopyridines over the Pd complex is significantly faster than from the bromo-substituted furanes and thiophenes previously studied.Debromination over Pd/C is faster than over the complex catalyst.Over both catalysts 3-bromopyridine debrominates faster than the 2-isomer.When molecular deuterium is used, the respective deuterated pyridines can be obtained.