Synthesis and in vitro antimalarial activity of some indoloquinolines

DOI: 10.1016/0223-5234(92)90152-Q

Source and publish data:

European Journal of Medicinal Chemistry p. 391 - 394 (1992)

Update date:2022-08-04

Topics:

Authors:

Go, M L Go, M L

Koh, H L

Ngiam, T L

Philipson, J D

Kirby, G C

et al. et al.

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Article abstract of DOI:10.1016/0223-5234(92)90152-Q

A series of indolo<3,2-c>quinolines (1b-e) was synthesized by Fischer indolization of 7-chloro-1,2,3,4-tetrahydroquinolin-4-one with the appropriate hydrazines (7b-e).Evaluation of in vitro antimalarisl activity was carried out against a chloroquine resis

Full text of DOI:10.1016/0223-5234(92)90152-Q

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