Biomedical Mass Spectrometry p. 483 - 487 (1978)
Update date:2022-08-05
Topics:
Foerster
Staehle
The structures of the methylated clonidine derivatives formed by on column methylation with trimethylanilinium hydroxide are revised. The almost exclusive formation of derivatives of phenylimino-N,N-dimethylimidazolidine structure is explained in terms of a fast kinetically controlled reaction of substrate anions. The reliability of a stable isotope dilution assay for clonidine is discussed in view of these results.
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Doi:10.1021/ja029823+
(2003)Doi:10.1039/P19740002097
(1974)Doi:10.1007/BF00799922
(1982)Doi:10.1007/BF00856074
()Doi:10.1021/ja01157a094
(1950)Doi:10.1039/jr9580001297
(1958)
