The structure of nitrones derived from amphetamines

Article abstract of DOI:10.1111/j.2042-7158.1974.tb09281.x

The nitrones obtained by mercuric oxide oxidation of N hydroxy N n propylamphetamine and N ethyl N hydroxyamphetamine were identified. The major in vitro metabolic product of fenfluramine is shown by a nuclear magnetic resonance study to be α methyl N [1 (m trifluoromethylbenzyl)ethyl]nitrone and not the isomer as claimed previously.