A new, highly stereoselective approach to pyrrolidines via overall 5-endo-trig cyclisations of homoallylic tosylamides

DOI: 10.1039/cc9960000915

Source and publish data:

Chemical Communications p. 915 - 916 (1996)

Update date:2022-08-04

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Authors:

Jones, Andrew D.

Knight, David W.

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Article abstract of DOI:10.1039/cc9960000915

Iodocyclisations of E-homoallylic tosylamides 7 lead to excellent yields of either 2,5-trans- or 2,5-cis-3-iodopyrrolidines (10 or 11), depending upon the reaction conditions.

Full text of DOI:10.1039/cc9960000915

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