Cycloalkanones. 6. Separation of hypocholesterolemic and antifertility activities in derivatives of 2,8 dibenzylcyclooctanone

Article abstract of DOI:10.1021/jm00238a023

Fluoro and hydroxy derivatives of 2,8 dibenzylcyclooctanone were prepared. Separation of antifertility activity from hypolipidemic and uterotropic effects was achieved with 2,8 bis (4 acetoxybenzyl)cyclooctanone. Some enhancement of the hypolipidemic effe