Probiotics. Antistaphylococcal and antifibrinolytic activities of omega amino and omega guanidinoalkanesulfonic acids

Article abstract of DOI:10.1021/jm00239a013

A series of ;. aminoalkanesulfonic acid and ω guanidinoalkanesulfonic acids was tested for antistaphylococcal and antifibrinolytic activities. Most of the former and one of the latter class gave better protection against Staphylococcus aureus infections in mice than 4 aminobutyryl L histidine. Most of the ω aminoalkanesulfonic acids showed antifibrinolytic activity, one of them having activity equal to or greater than that of aminocaproic acid, whereas none of the ω guanidinoalkanesulfonic acids had significant antifibrinolytic activity.